Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Decreasing Adverse Drug Reaction by This Combination |
Decreasing Adverse Drug Reaction |
Click to Show/Hide |
Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vitro Model |
KG-1a |
CVCL_1824
|
Adult acute myeloid leukemia |
Homo sapiens |
Hep-G2 |
CVCL_0027
|
Hepatocellular carcinoma |
Homo sapiens |
Experimental
Result(s) |
Olaparib interferes with anthracycline metabolism, and suggest that this phenomenon might be utilized for combating anthracycline resistance. |