Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Enhancing Drug Efficacy by This Combination |
Achieving Therapeutic Synergy |
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Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vitro Model |
T-cell populations from B6 mice |
Healthy |
Rattus norvegicus |
In-vivo Model |
Heterotopic vascularized heart transplantation was performed into the right cervical portion of the B6 mice. |
Experimental
Result(s) |
The combination of MMF and MZ showed mild synergistic effects in the inhibition of MLR and strong synergistic effects in a mouse heart transplantation model. |