Drug Combination Details
| General Information of the Combination (ID: C12423) | |||||
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| Name | Tea Polyphenols | + | Piperacillin + Tazobactam | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Tea Polyphenols NP Info | Drug Info | |||
| Structure |
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| Name | Drug Info | ||||
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| Disease |
Chronic obstructive pulmonary disease
[ICD-11: CA22]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Klebsiella pneumoniae | Microorganism model | Klebsiella pneumoniae | |||
| Experimental
Result(s) |
Tea polyphenols used in combination with commonly used antibiotics showed synergistic bactericidal effect against multidrug-resistant Klebsiella pneumoniae. | |||||
| References | ||||
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| Reference 1 | In-vitro antibacterial effect of tea polyphenols combined with common antibiotics on multidrug-resistant Klebsiella pneumoniae. Minerva Med. 2020 Dec;111(6):536-543. | |||
