Drug Combination Details
General Information of the Combination (ID: C28729) | |||||
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Name | Miltefosine NP Info | + | Lopinavi Drug Info | ||
Structure | + | ||||
Disease |
Leishmaniasis
[ICD-11: 1F54]
|
Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. Enhancing Drug Efficacy by This Combination | ||||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [1] | |||||
In-vivo Model | BALB/c mice were used in this study. | |||||
Experimental
Result(s) |
LPV- MFS combination therapy can be effective in the treatment of VL/HIV co-infected patients and provides data that can help to guide a possible therapeutic strategy in VL/HIV co-infection. |
References | ||||
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Reference 1 | Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum Infection: In vitro and in vivo Approaches. Front Cell Infect Microbiol. 2019 Jun 28;9:229. |