Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Enhancing Drug Efficacy by This Combination |
Achieving Therapeutic Synergy |
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Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vitro Model |
MIA PaCa-2 |
CVCL_0428
|
Pancreatic ductal adenocarcinoma |
Homo sapiens |
In-vivo Model |
Male Fishcher rats weighing 150-175 g were used in this study. |
Experimental
Result(s) |
Combination therapy offers a viable means of improving L-canavanine's intrinsic efficacy while decreasing the concentration of 5-FU required to produce the same cytotoxic effect. |