Drug Combination Details
General Information of the Combination (ID: C58456) | |||||
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Name | Acitretin NP Info | + | Methotrexate Drug Info | ||
Structure | + | ||||
Disease |
Plaque psoriasis
[ICD-11: EA90]
|
Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. Enhancing Drug Efficacy by This Combination | ||||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [1] | |||||
In-vivo Model | Male K14-VEGF mice (10 weeks old) were used in this study. | |||||
Experimental
Result(s) |
The acitretin and methotrexate combination therapy for psoriasis vulgaris achieves higher effectiveness and less liver fibrosis. |
References | ||||
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Reference 1 | The acitretin and methotrexate combination therapy for psoriasis vulgaris achieves higher effectiveness and less liver fibrosis. Pharmacol Res. 2017 Jul;121:158-168. |