Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Enhancing Drug Efficacy by This Combination |
Achieving Therapeutic Synergy |
Click to Show/Hide |
Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vivo Model |
Mouse was shaved with electric clippers and an approximately 4 cm2 area was marked and slightly abraded with sterile sandpaper before infection with 20 ul of suspension containing 1*106 C. albicans. |
Experimental
Result(s) |
It is very likely that, by damaging the cell wall, glycyrol helps fluconazole invade C. albicans more readily and attack fluconazole's target in the fungus membrane. |