Drug Combination Details
General Information of the Combination (ID: C73107) | |||||
---|---|---|---|---|---|
Name | Vincristine NP Info | + | Rituximab Drug Info | ||
Structure | + | ||||
Disease |
B-cell lymphoma
[ICD-11: 2A86]
|
Phase 3 | [1] | ||
Mantle cell lymphoma
[ICD-11: 2A85]
|
Investigative | [2] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
---|---|---|---|---|---|---|
α. Enhancing Drug Efficacy by This Combination | ||||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [2] | |||||
Biological
Regulation |
Increase | Tumor cell death | ||||
In-vitro Model | Ramos | CVCL_0597 | Burkitt lymphoma | Homo sapiens | ||
Experimental
Result(s) |
Rituximab synergizes with vincristine in the killing of Ramos Burkitt's lymphoma B cell line. |