Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Enhancing Drug Efficacy by This Combination |
Augmenting Drug Sensitivity |
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Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vitro Model |
SW1990 |
CVCL_1723
|
Pancreatic adenocarcinoma |
Homo sapiens |
AsPC-1 |
CVCL_0152
|
Pancreatic ductal adenocarcinoma |
Homo sapiens |
In-vivo Model |
SW1990 cells were injected subcutaneously into the right flank of nude mice using a 23-gauge needle at a 2*106 cells per mouse. |
Experimental
Result(s) |
Salinomycin combined with gemcitabine could eliminate the engraftment of human pancreatic cancer more effectively than the individual agents. |