Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Enhancing Drug Efficacy by This Combination |
Achieving Therapeutic Synergy |
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Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vitro Model |
M5076 |
CVCL_3997
|
Mouse ovarian histiocytic sarcoma |
Mus musculus |
In-vivo Model |
M5076 ovarian sarcoma (1 * 106 cells/mouse) were s.c. transplanted onto the backs of BDF1 mice. |
Experimental
Result(s) |
Theanine increased not only the antitumor activity on primary tumor but also the metastasis-suppressive efficacy of doxorubicin. |