Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Enhancing Drug Efficacy by This Combination |
Achieving Therapeutic Synergy |
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Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vitro Model |
MV4-11 |
CVCL_0064
|
Childhood acute monocytic leukemia |
Homo sapiens |
Ba/F3 |
CVCL_0161
|
Healthy |
Mus musculus |
MOLM-14 |
CVCL_7916
|
Adult acute myeloid leukemia |
Homo sapiens |
Experimental
Result(s) |
The addition of potent FLT3 inhibitors such as SU11248 to AML chemotherapy regimens could result in improved treatment results. |