Drug Combination Details
General Information of the Combination (ID: C92813) | |||||
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Name | Ginsenoside Rg3 NP Info | + | Oxaliplatin Drug Info | ||
Structure |
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Disease |
Hepatocellular carcinoma
[ICD-11: 2C12]
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Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. Enhancing Drug Efficacy by This Combination | ||||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [1] | |||||
Molecule(s)
Regulation |
Down-regulation | Expression | CCND1 | Molecule Info |
Pathway MAP
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Down-regulation | Expression | PCNA | Molecule Info |
Pathway MAP
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In-vitro Model | SMMC-7721 | CVCL_0534 | Hepatocellular carcinoma | Homo sapiens | ||
Experimental
Result(s) |
Cells treated with oxaliplatin+ ginsenoside enhanced the anti-tumor effect and may inhibit the proliferation and promoted apoptosis of hepatocellular carcinoma via regulating the expression of PCNA and cyclin D1. |
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