Molecule Details
| General Information of the Molecule | ||||
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| Name |
Mycobacterium Phosphatidylinositol synthase (MycB pssA)
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| Synonyms |
pssA; PtdIns synthase; CDP-diacylglycerol-inositol phosphatidyltransferase; PI synthase
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| Gene Name |
MycB pssA
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| Gene ID | ||||
| Sequence |
MIGKPRGRRGVNLQILPSAMTVLSICAGLTAIKFALEHQPKAAMALIAAAAILDGLDGRV
ARILDAQSRMGAEIDSLADAVNFGVTPALVLYVSMLSKWPVGWVVVLLYAVCVVLRLARY NALQDDGTQPAYAHEFFVGMPAPAGAVSMIGLLALKMQFGEGWWTSGWFLSFWVTGTSIL LVSGIPMKKMHAVSVPPNYAAALLAVLAICAAAAVLAPYLLIWVIIIAYMCHIPFAVRSQ RWLAQHPEVWDDKPKQRRAVRRASRRAHPYRPSMARLGLRKPGRRL Click to Show/Hide
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| Function |
Catalyzes the biosynthesis of phosphatidylinositol (ptdins) as well as ptdins:inositol exchange reaction. May thus act to reduce an excessive cellular ptdins content. The exchange activity is due to the reverse reaction of ptdins synthase.
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| Uniprot ID | ||||
| Pfam | ||||
| TTD ID | ||||
| Natural Product(s) of This Target | ||||
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| 1 | Myo-inositol | NP Info | Phase 2 | Fragaria x ananassa |
| References | ||||
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| Reference 1 | Phosphatidylinositol synthesis in mycobacteria. Biochim Biophys Acta. 1999 Jan 4;1436(3):437-50. | |||