Molecule Details
General Information of the Molecule | ||||
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Name |
Interleukin-20 receptor beta (IL20RB)
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Synonyms |
IL-20 receptor subunit beta; IL-20R-beta; IL-20RB; Fibronectin type III domain containing 6; FNDC6; IL-20R2
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Gene Name |
IL20RB
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Gene ID | ||||
Sequence |
MQTFTMVLEEIWTSLFMWFFYALIPCLLTDEVAILPAPQNLSVLSTNMKHLLMWSPVIAP
GETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQ TSAWSILKHPFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLVAYWRREPGAEEHV KMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGEAIPLVLALFAF VGFMLILVVVPLFVWKMGRLLQYSCCPVVVLPDTLKITNSPQKLISCRREEVDACATAVM SPEELLRAWIS Click to Show/Hide
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Function |
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
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Uniprot ID | ||||
Pfam | ||||
KEGG ID |
Drug(s) of This Target | ||||
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1 | GC-SF | Drug Info | Approved | Acute myelogenous leukemia |
References | ||||
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Reference 1 | IL-24: A new player in the pathogenesis of pro-inflammatory and allergic skin diseases. Allergol Int. 2020 Jul;69(3):405-411. |