Drug Combination Details
General Information of the Combination (ID: C28146) | |||||
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Name | Human plasma cholinesterase NP Info | + | Edrophonium Drug Info | ||
Structure | + | ||||
Disease |
Neuromuscular blockage
[ICD-11: NE60]
|
Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. Reversing Drug Resistance by This Combination | ||||||
Reversing Drug Resistance | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [1] | |||||
In-vivo Model | Clinical Trial | |||||
Experimental
Result(s) |
The edrophonium-PCHE combination significantly accelerated recovery of mivacurium-induced block compared with that observed with the use of individual antagonists. |
References | ||||
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Reference 1 | Edrophonium and human plasma cholinesterase combination for antagonism of mivacurium-induced neuromuscular block. Br J Anaesth. 1996 Sep;77(3):424-6. |