Natural Product (NP) Details
General Information of the NP (ID: NP6573) | |||||
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Name |
Human plasma cholinesterase
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Species Origin | Homo sapiens ... | Click to Show/Hide | |||
Homo sapiens | |||||
Disease | Neuromuscular blockage [ICD-11: NE60] | Phase 1 | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. A List of Drug(s) Whose Resistance can be Reversed by This NP | ||||||
Edrophonium | Myasthenia gravis | Click to Show/Hide the Molecular Data of This Drug | ||||
Reversing Drug Resistance | Click to Show/Hide | |||||
Representative Experiment Reporting the Effect of This Combination | [2] | |||||
Detail(s) | Combination Info click to show the detail info of this combination | |||||
In-vivo Model | Clinical Trial | |||||
Experimental
Result(s) |
The edrophonium-PCHE combination significantly accelerated recovery of mivacurium-induced block compared with that observed with the use of individual antagonists. |