Drug Combination Details
General Information of the Combination (ID: C29576) | |||||
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Name | Tretinoin | + | Hydroquinone + Fluocinolone acetonide | ||
Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
Name | Tretinoin NP Info | Drug Info | |||
Structure | |||||
Name | Drug Info | ||||
Structure | |||||
Disease |
Acquired hypermelanosis
[ICD-11: ED60]
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Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. Enhancing Drug Efficacy by This Combination | ||||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [1] | |||||
In-vivo Model | Clinical trial | |||||
Experimental
Result(s) |
Combination therapy with hydroquinone, tretinoin, and fluocinolone is the most cost-effective treatment when compared with any of its dyads or with hydroquinone alone. |
References | ||||
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Reference 1 | Cost-effectiveness of a hydroquinone/tretinoin/fluocinolone acetonide cream combination in treating melasma in the United States. J Dermatolog Treat. 2010 Sep;21(5):276-81. |