Drug Combination Details
General Information of the Combination (ID: C57775) | |||||
---|---|---|---|---|---|
Name | Neferine NP Info | + | Oxaliplatin Drug Info | ||
Structure | + | ||||
Disease |
Hepatocellular carcinoma
[ICD-11: 2C12]
|
Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
---|---|---|---|---|---|---|
α. Enhancing Drug Efficacy by This Combination | ||||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [2] | |||||
Molecule(s)
Regulation |
Up-regulation | Expression | CDH1 | Molecule Info |
Pathway MAP
|
|
Experimental
Result(s) |
Snail overexpression or TGF-Beta1-induced EMT attenuated Neferine-mediated OXA sensitization in HCC. | |||||
Experiment 2 Reporting the Effect of This Combination | [1] | |||||
Molecule(s)
Regulation |
Down-regulation | Expression | VIM | Molecule Info |
Pathway MAP
|
|
Experimental
Result(s) |
Snail overexpression or TGF-Beta2-induced EMT attenuated Neferine-mediated OXA sensitization in HCC. |