Drug Combination Details
General Information of the Combination (ID: C90784) | |||||
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Name | Colistin NP Info | + | Niclosamide Drug Info | ||
Structure | + | ||||
Disease |
Pneumonia
[ICD-11: CA40]
|
Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. Reversing Drug Resistance by This Combination | ||||||
Reversing Drug Resistance | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [1] | |||||
Biological
Regulation |
Increase | Zeta potential | ||||
In-vitro Model | Acinetobacter baumannii | Microorganism model | Acinetobacter baumannii | |||
Klebsiella pneumoniae | Microorganism model | Klebsiella pneumoniae | ||||
Experimental
Result(s) |
Niclosamide has potentiated the effect of colistin against Col-S and Col-R A. |