Drug Combination Details
General Information of the Combination (ID: C90798) | |||||
---|---|---|---|---|---|
Name | Pentostatin + Cladribine | + | Rituximab | ||
Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
Name | Pentostatin NP Info | Drug Info | |||
Structure | |||||
Name | Cladribine NP Info | ||||
Structure | |||||
Disease |
Chronic lymphocytic leukaemia
[ICD-11: 2A82]
|
Investigative | [1] |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
---|---|---|---|---|---|---|
α. Enhancing Drug Efficacy by This Combination | ||||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Experiment 1 Reporting the Effect of This Combination | [1] | |||||
Experimental
Result(s) |
The combination of a purine analog with rituximab was safe and effective for patients with recurrent HCL. |
References | ||||
---|---|---|---|---|
Reference 1 | Rituximab with pentostatin or cladribine: an effective combination treatment for hairy cell leukemia after disease recurrence. Leuk Lymphoma. 2011 Jun;52 Suppl 2:75-8. |