Drug Combination Details
| General Information of the Combination (ID: C00130) | |||||
|---|---|---|---|---|---|
| Name | Procyanidin NP Info | + | 5-fluorouracil Drug Info | ||
| Structure |
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+ |
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| Disease |
Colon cancer
[ICD-11: 2B90]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Augmenting Drug Sensitivity | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Caco-2 | CVCL_0025 | Colon adenocarcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Procyanidin enhances the impact of 5-Fluorouracil chemotherapy on Caco-2 human colon cancer cells. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Low molecular weight procyanidins from grape seeds enhance the impact of 5-Fluorouracil chemotherapy on Caco-2 human colon cancer cells. PLoS One. 2014 Jun 6;9(6):e98921. | |||
