Drug Combination Details
| General Information of the Combination (ID: C03873) | |||||
|---|---|---|---|---|---|
| Name | Morroniside NP Info | + | Diosgenin Drug Info | ||
| Structure |
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+ |
|
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| Disease |
Cardiomyopathy
[ICD-11: BC43]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Up-regulation | Cleavage | CASP3 | Molecule Info |
Pathway MAP
|
|
| Experimental
Result(s) |
Combination of morroniside and diosgenin prevents high glucose-induced cardiomyocytes apoptosis. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Combination of Morroniside and Diosgenin Prevents High Glucose-Induced Cardiomyocytes Apoptosis. Molecules. 2017 Jan 19;22(1):163. | |||
