| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
| α. Enhancing Drug Efficacy by This Combination |
| Achieving Therapeutic Synergy |
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| Experiment 1 Reporting the Effect of This Combination |
[1] |
| In-vitro Model |
B16 |
CVCL_F936
|
Mouse melanoma |
Mus musculus |
| In-vivo Model |
B16TK cells and B16 cells were mixed at a 3:7 ratio and subcutaneously inoculated the right flank of the pathogen-free C57BL/6 J mice (18-22 g). |
Experimental
Result(s) |
Resveratrol could synergistically enhance the killing effect of TK/GCV suicide gene system in melanoma B16 cells and transplanted melanoma. |
