Drug Combination Details
| General Information of the Combination (ID: C12957) | |||||
|---|---|---|---|---|---|
| Name | Alitretinoin NP Info | + | 5-fluorouracil Drug Info | ||
| Structure |
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+ |
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| Disease |
Darier disease
[ICD-11: EC20]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Experimental
Result(s) |
Alitretinoin combined with topical 5-FU seems to be an interesting option in patients with DD, as it can allow a durable clinically complete remission with a good tolerance. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Combination of alitretinoin and topical 5-fluorouracil in Darier disease. JAAD Case Rep. 2018 Dec 11;5(1):75-77. | |||
