Drug Combination Details
| General Information of the Combination (ID: C21165) | |||||
|---|---|---|---|---|---|
| Name | Colchicine NP Info | + | Dapsone Drug Info | ||
| Structure |
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+ |
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| Disease |
Hypertriglyceridaemia
[ICD-11: 5C80]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Male Sprague-Dawley (SD) rats weighing 200-220 g were used in this study. | |||||
| Experimental
Result(s) |
Colchicine combined with atorvastatin may have stronger protective effects on improving endothelial function and ameliorating inflammation in rats with hyperlipidemia. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Synergistic effects of colchicine combined with atorvastatin in rats with hyperlipidemia. Lipids Health Dis. 2014 Apr 17;13:67. | |||
