Drug Combination Details

General Information of the Combination (ID: C24753)
Name Beta carotene   NP Info  + 1,25-dihydroxyvitamin D3   Drug Info 
Structure +
Disease
Esophageal cancer [ICD-11: 2B70]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vitro Model EC9706 CVCL_E307 Esophageal squamous cell carcinoma Homo sapiens
                    Experimental
                    Result(s)		 These two agents in combination synergistically inhibited cell growth and induced apoptosis.
References
Reference 1 Inhibition of proliferation and induction of apoptosis by the combination of Beta-carotene and 1,25-dihydroxyvitamin D3 in human esophageal cancer EC9706 cells. Asian Pac J Cancer Prev. 2012;13(12):6327-32.
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