Drug Combination Details
| General Information of the Combination (ID: C25772) | |||||
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| Name | Mupirocin + Clavulanate | + | Amoxicillin | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Mupirocin NP Info | Drug Info | |||
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| Name | Clavulanate NP Info | ||||
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Staphylococcus aureus | Microorganism model | Staphylococcus aureus | |||
| Experimental
Result(s) |
Mupirocin and amoxicillin-clavulanate were synergistic against 9 of 49 (18%) strains of methicillin-resistant and methicillin-susceptible Staphylococcus aureus and coagulase-negative staphylococci (CNS). | |||||
