| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
| α. Enhancing Drug Efficacy by This Combination |
| Achieving Therapeutic Synergy |
Click to Show/Hide |
| Experiment 1 Reporting the Effect of This Combination |
[1] |
| In-vitro Model |
Ba/F3 |
CVCL_0161
|
Healthy |
Mus musculus |
| WEHI-265.1 |
CVCL_3620
|
Mouse leukemia |
Mus musculus |
| In-vivo Model |
Ba/F3-insH cell line xenografts were generated by injecting 5*106 cells in 50% matrigel into six-to eight- week old male nu/nu nude mice. |
Experimental
Result(s) |
The combination of ellagic acid with erlotinib has synergistic effects against EGFR H773_V774 insH mutation. |
