Drug Combination Details
| General Information of the Combination (ID: C29934) | |||||
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| Name | Apocynin | + | Captopril + Losartan | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Apocynin NP Info | Drug Info | |||
| Structure |
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| Name | Drug Info | ||||
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| Disease |
Chronic kidney disease
[ICD-11: GB61]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | A 5/6 nephrectomy mouse model of CDK was used in this study. | |||||
| Experimental
Result(s) |
Apocynin in conjunction with a coadjuvant for modulating blood pressure may be useful for controlling the progression of CRF. | |||||
| References | ||||
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| Reference 1 | Apocynin combined with drugs as coadjuvant could be employed to prevent and/or treat the chronic kidney disease. Ren Fail. 2018 Nov;40(1):92-98. | |||
