Drug Combination Details
| General Information of the Combination (ID: C31212) | |||||
|---|---|---|---|---|---|
| Name | Farnesol | + | Micafungin + Caspofungin | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Farnesol NP Info | Drug Info | |||
| Structure |
|
|
|||
| Name | Drug Info | ||||
| Structure |
|
|
|||
| Disease |
Candidosis
[ICD-11: 1F23]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Candida parapsilosis isolates | Microorganism model | Candida parapsilosis | |||
| Candida parapsilosis ATCC 22019 | Microorganism model | Candida parapsilosis | ||||
| Experimental
Result(s) |
Caspofungin and micafungin in combination with farnesol showed synergistcant interaction against Candida parapsilosis biofilms. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Effect of caspofungin and micafungin in combination with farnesol against Candida parapsilosis biofilms. Int J Antimicrob Agents. 2016 Apr;47(4):304-10. | |||
