Drug Combination Details
| General Information of the Combination (ID: C34640) | |||||
|---|---|---|---|---|---|
| Name | Paroxetine NP Info | + | Everolimus Drug Info | ||
| Structure |
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+ |
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| Disease |
Ischemic stroke
[ICD-11: 8B11]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | SH-SY5Y | CVCL_0019 | Neuroblastoma | Homo sapiens | ||
| Experimental
Result(s) |
Combination treatment with Everolimus and Paroxetine showed synergistic post-ischemic neuroprotective efficacy. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | The Synergistic Combination of Everolimus and Paroxetine Exerts Post-ischemic Neuroprotection In Vitro. Cell Mol Neurobiol. 2018 Oct;38(7):1383-1397. | |||
