Drug Combination Details
| General Information of the Combination (ID: C38304) | |||||
|---|---|---|---|---|---|
| Name | Doxercalciferol NP Info | + | KML001 Drug Info | ||
| Structure |
|
+ |
|
||
| Disease |
Acute lymphoblastic leukemia
[ICD-11: 2B33]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Experimental
Result(s) |
A combination of KML001 with doxercalciferol showed a synergistic effect on ALL cell lines. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | KML001 and doxercalciferol induce synergistic antileukemic effect in acute lymphoid leukemia cells. Oncol Rep. 2017 Jul;38(1):481-487. | |||
