| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
| α. Enhancing Drug Efficacy by This Combination |
| Achieving Therapeutic Synergy |
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| Experiment 1 Reporting the Effect of This Combination |
[1] |
| In-vitro Model |
Cells derived from glioblastoma multiforme patients |
Glioblastoma multiforme |
Homo sapiens |
| In-vivo Model |
For in vivo experiments, CSCs (5 * 104 cells) were implanted intracranially into 10 week-old female C.B17-lcr SCID mice. |
Experimental
Result(s) |
Arsenic trioxide drastically enhanced the anti-proliferative effect of 10058F4 but not apoptotic effects. |
