Drug Combination Details
| General Information of the Combination (ID: C39034) | |||||
|---|---|---|---|---|---|
| Name | Topiramate NP Info | + | Diethylpropion Drug Info | ||
| Structure |
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+ |
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| Disease |
Obesity
[ICD-11: 5B81]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Experimental
Result(s) |
Low doses of the diethylpropion + topiramate combination can potentiate the anorectic effect of individual drugs with a better safety profile. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Anorectic efficacy and safety of the diethylpropion-topiramate combination in rats. Drug Dev Res. 2018 Aug;79(5):225-233. | |||
