Drug Combination Details

General Information of the Combination (ID: C45460)
Name Anidulafungin   NP Info  + Posaconazole   Drug Info 
Structure +
Disease
Aspergillosis [ICD-11: 1F20]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vitro Model Aspergillus fumigatus Microorganism model Aspergillus fumigatus
                    In-vivo Model Six-week-old female Swiss mice were immunosuppressed with a combination of cyclophosphamide and cortisone acetate.
                    Experimental
                    Result(s)		 The PSC and AFG combination therapy was highly effective and should be evaluated in larger-scale experiments.
References
Reference 1 Evaluation of the efficacy of a posaconazole and anidulafungin combination in a murine model of pulmonary aspergillosis due to infection with Aspergillus fumigatus. Diagn Microbiol Infect Dis. 2018 Jan;90(1):40-43.
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