Drug Combination Details
| General Information of the Combination (ID: C45627) | |||||
|---|---|---|---|---|---|
| Name | Bisdemethoxycurcumin NP Info | + | Gentamicin Drug Info | ||
| Structure |
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+ |
|
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Down-regulation | Expression | UL54 | Molecule Info | ||
| In-vitro Model | Staphylococcus aureus strains | Microorganism model | Staphylococcus aureus | |||
| Experimental
Result(s) |
Antimicrobial effect of BDMC combined with antibiotics was superior to treatment with that of a single agent alone. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | The Mechanism of Bisdemethoxycurcumin Enhances Conventional Antibiotics against Methicillin-Resistant Staphylococcus aureus. Int J Mol Sci. 2020 Oct 26;21(21):7945. | |||
