Drug Combination Details
| General Information of the Combination (ID: C46840) | |||||
|---|---|---|---|---|---|
| Name | Arctigenin NP Info | + | Ultraviolet A irradiation Drug Info | ||
| Structure |
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+ |
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| Disease |
Healthy individual
[ICD-11: N.A.]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Up-regulation | Expression | PRKAA2 | Molecule Info |
Pathway MAP
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| In-vitro Model | Human mesenchymal stem cells derived from adipose tissue | Healthy | Homo sapiens | |||
| Experimental
Result(s) |
Arctigenin protects against ultraviolet-A-induced damage to stemness through inhibition of the NF-KappaB/MAPK pathway. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Arctigenin protects against ultraviolet-A-induced damage to stemness through inhibition of the NF-KappaB/MAPK pathway. Chem Biol Interact. 2018 Feb 25;282:63-68. | |||
