Drug Combination Details
| General Information of the Combination (ID: C48863) | |||||
|---|---|---|---|---|---|
| Name | Juglans regia NP Info | + | Oxacillin Drug Info | ||
| Structure |
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+ |
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Staphylococcus aureus | Microorganism model | Staphylococcus aureus | |||
| Streptococcus pyogenes | Microorganism model | Streptococcus pyogenes | ||||
| Escherichia coli | Microorganism model | Escherichia coli | ||||
| Salmonella enterica serovar Typhi | Microorganism model | Salmonella enterica | ||||
| Shigella species | Microorganism model | Shigella | ||||
| Salmonella Paratyphi A | Microorganism model | Salmonella Paratyphi | ||||
| Pseudomonas aeuginosa | Microorganism model | Pseudomonas aeruginosa | ||||
| Acinetobacter baumannii | Microorganism model | Acinetobacter baumannii | ||||
| Klebseilla pneumoniae | Microorganism model | Klebseilla pneumoniae | ||||
| Citrobacter freuendii | Microorganism model | Citrobacter freuendii | ||||
| Enterobacter cloacae | Microorganism model | Enterobacter cloacae | ||||
| Bacillus subtilis | Microorganism model | Bacillus subtilis | ||||
| Streptococcus pneumoniae | Microorganism model | Streptococcus pneumoniae | ||||
| Micrococcus | Microorganism model | Micrococcus | ||||
| Helicobacter pylori | Microorganism model | Helicobacter pylori | ||||
| Campylobacter jejuni | Microorganism model | Campylobacter jejuni | ||||
| Pasteurella multocida | Microorganism model | Pasteurella multocida | ||||
| Experimental
Result(s) |
Ten times reduction in MICs was observed against Staphylococcus aureus when used in combination with oxacillin. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Synergistic antimicrobial activity of Camellia sinensis and Juglans regia against multidrug-resistant bacteria. PLoS One. 2015 Feb 26;10(2):e0118431. | |||
