Drug Combination Details
| General Information of the Combination (ID: C49042) | |||||
|---|---|---|---|---|---|
| Name | Fosfomycin NP Info | + | Linezolid Drug Info | ||
| Structure |
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+ |
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Staphylococcus aureus strains | Microorganism model | Staphylococcus aureus | |||
| Experimental
Result(s) |
Linezolid combined with fosfomycin at 4x MIC showed the best synergistic antibacterial effect, and this effect was retained after 24 hours. | |||||
