Drug Combination Details
| General Information of the Combination (ID: C51354) | |||||
|---|---|---|---|---|---|
| Name | Diallyl disulfide NP Info | + | N-acetylcysteine Drug Info | ||
| Structure |
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+ |
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| Disease |
Acetaminophen-induced cataract
[ICD-11: 9B10]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | C57BL/6 mice were used in this study. | |||||
| Experimental
Result(s) |
Treatment with DADS and NAC together effectively protected the liver. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Prevention of acetaminophen-induced cataract by a combination of diallyl disulfide and N-acetylcysteine. J Ocul Pharmacol Ther. 1998 Aug;14(4):345-55. | |||
