Drug Combination Details
| General Information of the Combination (ID: C51443) | |||||
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| Name | Mycophenolate mofetil + Corticosteroid | + | Cyclosporin | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Mycophenolate mofetil NP Info | Drug Info | |||
| Structure |
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| Name | Corticosteroid NP Info | ||||
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| Disease |
Nephrotic syndrome
[ICD-11: GB41]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Clinical trial | |||||
| Experimental
Result(s) |
Triple immunosuppressive therapy significantly reduced proteinuria and preserved renal function in refractory NS patients. | |||||
| References | ||||
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| Reference 1 | Combination treatment with corticosteroid, cyclosporine A, and mycophenolate in refractory nephrotic syndrome. Clin Nephrol. 2011 Jun;75(6):511-7. | |||
