Drug Combination Details
| General Information of the Combination (ID: C55065) | |||||
|---|---|---|---|---|---|
| Name | Genistein NP Info | + | Trastuzumab Drug Info | ||
| Structure |
|
+ |
|
||
| Disease |
Breast cancer
[ICD-11: 2C60]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | BT-474 | CVCL_0179 | Invasive breast carcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Genistein significantly enhanced the antitumoral effect of trastuzumab on BT-474 breast cancer cells in vitro. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Additive effects of trastuzumab and genistein on human breast cancer cells. Anticancer Drugs. 2011 Mar;22(3):253-61. | |||
