Drug Combination Details
| General Information of the Combination (ID: C58456) | |||||
|---|---|---|---|---|---|
| Name | Acitretin NP Info | + | Methotrexate Drug Info | ||
| Structure |
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+ |
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| Disease |
Plaque psoriasis
[ICD-11: EA90]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Male K14-VEGF mice (10 weeks old) were used in this study. | |||||
| Experimental
Result(s) |
The acitretin and methotrexate combination therapy for psoriasis vulgaris achieves higher effectiveness and less liver fibrosis. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | The acitretin and methotrexate combination therapy for psoriasis vulgaris achieves higher effectiveness and less liver fibrosis. Pharmacol Res. 2017 Jul;121:158-168. | |||
