Drug Combination Details
| General Information of the Combination (ID: C58912) | |||||
|---|---|---|---|---|---|
| Name | Genistein NP Info | + | Thearubigin Drug Info | ||
| Structure |
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+ |
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| Disease |
Prostate cancer
[ICD-11: 2C82]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Biological
Regulation |
Induction | Cell cycle arrest in G2/M phase | ||||
| In-vitro Model | PC-3 | CVCL_0035 | Prostate carcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Thearubigin and genistein combination showed synergistic effects on human prostate tumor cell (PC-3) growth via cell cycle arrest. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Synergistic effects of thearubigin and genistein on human prostate tumor cell (PC-3) growth via cell cycle arrest. Cancer Lett. 2000 Apr 3;151(1):103-9. | |||
