Drug Combination Details
| General Information of the Combination (ID: C63861) | |||||
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| Name | Fluoroorotic acid | + | Cisplatin + 5-fluorouracil | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Fluoroorotic acid NP Info | Drug Info | |||
| Structure |
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| Name | Drug Info | ||||
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| Disease |
Colon cancer
[ICD-11: 2B90]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Experimental
Result(s) |
Weekly administration of 5-FU/FA/cisplatin is an active and well-tolerated regimen. Toxicity is manageable and allows chemotherapy on an outpatient basis without hydration program as required when cisplatin is used at the dose of 50 mg/m2. | |||||
