Drug Combination Details
| General Information of the Combination (ID: C64666) | |||||
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| Name | 1,8-cineole + Clavulanate | + | Amoxicillin | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | 1,8-cineole NP Info | Drug Info | |||
| Structure |
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| Name | Clavulanate NP Info | ||||
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| Disease |
Osteomyelitis
[ICD-11: FB84]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Forty-two female New Zealand white rabbits (5-6 weeks old), weighing between 1.2 and 1.8 kg were used in this study. | |||||
| Experimental
Result(s) |
The combination of the AMC with gentamicin did not induce a synergistic effect, whereas the combination of the two antibiotics with 1,8-cineole did. | |||||
