Drug Combination Details
| General Information of the Combination (ID: C68965) | |||||
|---|---|---|---|---|---|
| Name | Anidulafungin NP Info | + | Amphotericin B Drug Info | ||
| Structure |
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+ |
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| Disease |
Fungal infection
[ICD-11: 1F29-1F2F]
|
Phase 4 | [1] | ||
|
Candidosis
[ICD-11: 1F23]
|
Investigative | [2] | |||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [2] | |||||
| Experimental
Result(s) |
Anidulafungin with amphotericin B results in a synergistic effect against C. albicans and C. glabrata biofilms at serum concentrations of the drugs, but showed no interaction against C. tropicalis and C. parapsilosis complex. | |||||
