Drug Combination Details
| General Information of the Combination (ID: C70557) | |||||
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| Name | 1,8-cineole + 1,8-cineole | + | Chlorhexidine | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | 1,8-cineole NP Info | Drug Info | |||
| Structure |
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| Name | 1,8-cineole NP Info | ||||
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | Staphylococcus aureus | Microorganism model | Staphylococcus aureus | |||
| Pseudomonas aeruginosa | Microorganism model | Pseudomonas aeruginosa | ||||
| Escherichia coli | Microorganism model | Escherichia coli | ||||
| Candida albicans | Microorganism model | Candida albicans | ||||
| Experimental
Result(s) |
CHG may be combined with either crude EO or its major component 1,8-cineole for enhanced, synergistic antimicrobial activity against a wide range of microorganisms in planktonic and biofilm modes of growth. | |||||
