Drug Combination Details
| General Information of the Combination (ID: C72298) | |||||
|---|---|---|---|---|---|
| Name | Breviscapine NP Info | + | Cisplatin Drug Info | ||
| Structure |
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+ |
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| Disease |
Urinary system disease
[ICD-11: GC2Z]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Decreasing Adverse Drug Reaction by This Combination | ||||||
| Decreasing Adverse Drug Reaction | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Equal numbers of male and female Kunming mice, weighting 18-22 g were used in this study. | |||||
| Experimental
Result(s) |
Breviscapine can reduce cisplatin-induced renal toxicity in mice. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Therapeutic effect and mechanism of breviscapine on cisplatin-induced nephrotoxicity in mice. Asian Pac J Trop Med. 2015 Oct;8(10):873-7. | |||
