Drug Combination Details
| General Information of the Combination (ID: C72640) | |||||
|---|---|---|---|---|---|
| Name | Methyl jasmonate NP Info | + | 3-bromopyruvate Drug Info | ||
| Structure |
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+ |
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| Disease |
Breast cancer
[ICD-11: 2C60]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | 4T1 | CVCL_0125 | Malignant neoplasms | Mus musculus | ||
| In-vivo Model | BALB/c inbred female mice were used in this study. | |||||
| Experimental
Result(s) |
This combination therapy didn't have any noticeable side effects on kidney, liver, and immune system and body weight. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Effect of methyl jasmonate and 3-bromopyruvate combination therapy on mice bearing the 4 T1 breast cancer cell line. J Bioenerg Biomembr. 2020 Apr;52(2):103-111. | |||
